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Drugs which inhibit CYP 3A4 (e.g., ketoconazole, itraconazole, ritonavir, indinavir, macrolide antibiotics s uch as erythromycin ) have the prednisone potential to result in increased plasma concentrations of corticosteroids. Indicated immunization uses procedures may be uses undertaken in patients receiving nonimmunosuppressive doses of corticosteroids as replacement prednisone therapy (e.g., for Addison's disease). Prednisone is also for dogs and cats as a prednisone corticosteroid used to treat inflammatory arthritis and boost the prednisone immune prednisone system. Antitubercular drugs Serum concentrations of is oniazid may be decreased. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Endocrine Adrenal insufficiency-greatest potential caused by high potency glucocorticoids with long duration of action (associated symptoms include; arthralgias, buffalo hump, dizziness, life-threatening hypotension, nausea, severe tiredness or weakness amenorrhea, postmenopausal bleeding or other uses menstrual irregularities, decreased carbohydrate and glucose tolerance, development. Collagen Diseases During an exacerbation or as maintenance therapy in selected cases of: systemic lupus erythematosus, systemic dermatomyositis ( polymyositis acute rheumatic carditis. Ophthalmic Diseases Severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa such as: allergic corneal marginal ulcers, herpes zoster ophthalmicus, anterior segment inflammation, diffuse posterior uveitis and choroiditis, sympathetic ophthalmia, allergic conjunctivitis, keratitis, chorioretinitis, optic neuritis, iritis and iridocyclitis. Kidney disease, thyroid disease, stomach and intestinal problems, some people with. The drug also can also effectively reduce swelling and redness. Prednisone may increase your risk for osteoporosis, a prednisone disease that weakens bones so much that they become fragile and break easily. Gastrointestinal Steroids should be used with caution in active or latent peptic ulcers, diverticulitis, fresh intestinal anastomoses, and nonspecific ulcerative colitis, since they may increase the risk of a perforation. Consult your doctor before breast-feeding. Ask your vet about weaning your dog off of them slowly. Metabolic clearance of corticosteroids is decreased in hypothyroid patients and increased in hyperthyroid patients. Antibiotics Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance (see Hepatic Enzyme Inducers, Inhibitors and Substrates ). The diurnal rhythm of the HPA axis is lost in Cushing's disease, a syndrome of adrenocortical hyperfunction characterized prednisone by obesity with centripetal fat uses distribution, thinning of the skin with easy bruisability, muscle wasting with weakness, hypertension, latent diabetes, osteoporosis, electrolyte imbalance, etc. Neuro-Psychiatric Although controlled clinical trials have shown corticosteroids to be effective in speeding the resolution of acute exacerbations uses of multiple sclerosis, they do not show that they affect uses the ultimate outcome or natural history of the disease. Infections associated with corticosteroids and immunosuppressive therapy. Exogenous corticosteroids suppress adrenocorticoid activity uses the least when given at the time of maximal activity (am) for single dose administration. Uses, Benefits, and Working Copyright 2019 TabletTree, Inc. Consult your doctor or pharmacist for more information. Indications, digestive Disease Myths Slideshow Pictures 10 Facts About the Amazing Brain. It is important to keep the period of initial suppressive dose as brief as possible particularly when subsequent use of alternate day therapy is intended. Currently available brand names include Sterapred, Sterapred DS, and Prednisone Intensol. Alternate day therapy is a therapeutic technique primarily designed for patients in whom long-term pharmacologic corticoid therapy is anticipated. These side effects might include the following: Increased thirst. Contraindications Prednisone tablets are contraindicated in systemic fungal infections and known hypersensitivity to components. If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Prednisone medicine then it may not be safe to drive a vehicle or operate heavy machinery. Current recommendations uses suggest that all interventions be initiated in any patient in whom glucocorticoid therapy with at least the equivalent of 5 mg of prednisone for at least 3 months is anticipated; in addition, sex hormone replacement therapy (combined estrogen. Consult your doctor if you have been exposed to an infection or for more details. You may also report side-effects to your local food and drug administration authority. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Your vet will strive to find the lowest dose possible while still maintaining your dogs health.